Read the clindamycin obesity Results-at-a-Glance summary.

Clindamycin is a medicine commonly used to treat a variety of infections, including skin and bone infections. Because the body easily absorbs clindamycin into fat, a child’s obesity status may affect the amount of the medicine they need to treat infections. Researchers performed this study to learn how children with obesity process clindamycin compared to children without obesity.

Read the topiramate Results-at-a-Glance summary.

Topiramate is a medicine used to treat seizures in adults and children. The recommended amount of topiramate children should receive is based on their weight. However, it was not known whether a child’s obesity status affects how they process topiramate.Researchers performed this study to learn how children with obesity process topiramate compared to children without obesity. They also wanted to learn the safest, most effective amount of the medicine they should receive.

Read the ondansetron Results-at-a-Glance summary.

Most breastfeeding women take at least one prescription medication. Some mothers worry that medicines they take might get into their breast milk and affect their baby. This study by the PTN, called Commonly used drugs during lactation and infant exposure (CUDDLE) was needed to learn how breastfeeding infants are exposed to medicine taken by breastfeeding women. Women who are breastfeeding may take ondansetron to treat nausea and vomiting.