The PTN conducts Phase 1-4 trials and data-based studies across a broad range of conditions affecting pediatric patients.
ONGOING STUDIES
Study Name | Status | Population | Condition | Study Type | ClinicalTrials.gov ID |
---|---|---|---|---|---|
Antibiotic safety (SCAMP) | Enrolling | Premature infants | Intra-abdominal infections | Interventional | NCT01994993 |
Anti-epileptic obesity | Enrolling | Obese children | Epilepsy | Interventional | NCT02993861 |
Baby TAPE | Analysis ongoing | Newborns and young infants | NA (Weight estimation tool) | Interventional | |
Baby TAPE III | Enrolling | Newborns and young infants | NA (Weight estimation tool) | Interventional | |
Caffeine | Analysis ongoing | Premature infants and infants | Bronchopulmonary dysplasia | Retrospective data collection | |
Commonly used drugs during lactation and infant exposure (CUDDLE) | Enrolling | Breastfeeding mothers and infants | Various (drugs administered regularly by physicians) | Interventional | NCT03511118 |
Furosemide | Enrolling | Premature infants | Bronchopulmonary dysplasia | Interventional | NCT02527798 |
Long-term Antipsychotic Pediatric Safety Trial (LAPS) | Enrolling | Children | Mono-antipsychotic therapies | Observational | NCT03522168 |
Midazolam | Analysis ongoing | Children (≥2 y) | Seizures | Retrospective data analysis | NA |
Personal protective equipment (PPE) | Enrollment closed | Research doctors and nurses | Evaluating impact of various PPE | Interventional | NA |
POPS | Enrolling | Children (<21 y) | Various (drugs administered regularly by physicians) | Observational | NCT01431326 |
Sildenafil II | Enrolling | Premature infants | Bronchopulmonary dysplasia | Phase 2 | NCT03142568 |
Timolol | Enrolling | Infants | Infantile hemangioma | Phase 2 | NCT02913612 |
Trimethoprim-sulfamethoxazole and clindamycin | Analysis ongoing | Children | Skin and soft tissue infections | Data from 3 protocols | NCT01431326, NCT01728363, NCT01744730 |
COMPLETED STUDIES
Study Name | Status | Population | Condition | Study Type | ClinicalTrials.gov ID |
---|---|---|---|---|---|
Acyclovir | Closed; clinical study report submitted to FDA | Premature infants | Systemic infection | Phase 1 | NCT00942084 |
Acyclovir retrospective | Closed; clinical study report submitted to FDA | Infants | Herpes simplex virus | Retrospective data collection | |
Ampicillin | Published; clinical study report submitted to FDA | Infants | Bacterial infections including sepsis and meningitis | Secondary data analysis | |
Anti-staph trio | Completed | Premature infants | Staphylococcal infections | Interventional | NCT01728363 |
Clindamycin obesity | Clinical study report submitted to FDA | Obese children | Staphylococcal infections | Phase 1 | NCT01744730 |
Diuretic safety | Clinical study report submitted to FDA | Infants | Bronchopulmonary dysplasia | Retrospective observational | NA |
Fluconazole safety | Published; clinical study report submitted to FDA | Infants | Candidemia | Meta-analysis | NCT00734539 |
Hydroxyurea | Clinical study report submitted to FDA | Children (2-4 y) | Sickle cell anemia or sickle beta-zero thalassemia | Phase 2 | NCT01506544 |
Lisinopril PK | Completed; label changed | Children and adolescents (2-17 y) | Kidney transplant; high blood pressure | Interventional | NCT01491919 |
Lorazepam | Completed; label changed | Children and adolescents (3 mo-18 y) | Status epilepticus (Status 1) | Interventional | NCT00114569 |
Lorazepam or diazepam | Clinical study report submitted to FDA | Children and adolescents (3 mo-18 y) | Pediatric status epilepticus (Status 2) | Interventional | NCT00621478 |
Meropenem | Completed; label changed | Infants | Intra-abdominal infections | Interventional | NCT00621192 |
Methadone | Completed | Children | Opiate withdrawal | Observational | NCT01945736 |
Metronidazole | Published; clinical study report submitted to FDA | Premature infants | Serious infection caused by anaerobic bacteria | Interventional | NCT01222585 |
Obesity informatics | Published | Children | Various | Systematic literature review | NA |
Pantoprazole | Completed | Obese children | GERD | Phase 1 | NCT02186652 |
Pediatrix meta-analysis | Published; clinical study report submitted to FDA | Infants | Various | Meta-analysis | NA |
Sildenafil | Completed | Premature infants | Bronchopulmonary dysplasia | Phase 1 | NCT01670136 |
TAPE | Published; clinical study report submitted to FDA | Children (2-16 y) | NA (Mercy Method™ for weight estimation) | Observational | NCT01507090 |