Read the lorazepam Results-at-a-Glance summary.

Status epilepticus (SE) is a serious condition that affects the brain. SE can be caused by medical conditions, illnesses, or injuries. A preferred treatment for SE is lorazepam. However, lorazepam is not approved by the FDA for children under 18 years old. This summary is for a study performed by the Pediatric Trials Network (PTN). The study was needed to find out how children with SE process lorazepam.

Read the oxcarbazepine Results-at-a-Glance summary.

Oxcarbazepine is a medicine that is approved by the U.S. Food and Drug Administration (FDA) for treating seizures in adults and children older than two years. However, guidance for children who have obesity was lacking. This study was needed to learn how a child’s obesity status affects the way they process oxcarbazepine.

Read diazepam Results-at-a-Glance summary.

Diazepam is a medicine approved by the U.S. Food and Drug Administration (FDA) for treating severe seizures in children. However, the most safe and effective dosage of diazepam for children was unknown.