Read the topiramate Results-at-a-Glance summary.

Topiramate is a medicine used to treat seizures in adults and children. The recommended amount of topiramate children should receive is based on their weight. However, it was not known whether a child’s obesity status affects how they process topiramate.Researchers performed this study to learn how children with obesity process topiramate compared to children without obesity. They also wanted to learn the safest, most effective amount of the medicine they should receive.