The Institutional Development Award (IDeA) is a congressionally mandated program helping to build research capacity by supporting research, faculty development, and infrastructure improvements in states with low National Institutes of Health (NIH) funding levels. Children, racial, and ethnic minorities, rural populations, and patients of low socioeconomic status are underrepresented in clinical research, which limits the generalizability of results. To address this gap, 17 institutions were awarded funding in 2016 to establish the IDeA States Pediatric Clinical Trials Network (ISPCTN) by the NIH’s Environmental Influences on Child Health Outcomes Program.