Pharmaceutical Regulatory Affairs • April 2019
Zimmerman KO, Benjamin DK ,Becker ML, Anand R, Hornik CP
Obesity is a major public health problem that can affect drug disposition and dosing, particularly in vulnerable pediatric populations. Despite potentially detrimental consequences from inappropriately dosed drugs in children with obesity, drug product labels largely fail to include dosing or guidance specific to this population. Using data from the PTN, this study explored possible ways to improve drug labeling in children with obesity.