Weight is the foremost marker of health and health outcomes in infants. A weighing scale remains the universal gold standard for obtaining weight in children and is highlighted by the World Health Organization as one of four essential pieces of equipment needed when caring for newborns. However, the vast majority of healthcare providers in remote, resource-constrained settings simply do not have access to functional, calibrated scales with the precision necessary to accurately determine weight. Many critically ill newborns in the U.S. suffer similar challenges when it comes to weight assessment. For infants receiving care in a neonatal intensive care unit, it can be nearly impossible to remove or account for the weight of life-sustaining medical equipment prior to obtaining a scale-based weight. The relative error introduced by such equipment can significantly affect the safety profile of the medicines these infants receive.
Importantly, there is no other patient population for whom more calculation and manipulation of drug doses occurs than in the newborn—from prescribing and transcribing the dose to diluting, compounding, dispensing, and administering the final formulation. As a result, dosing errors represent the most common type of medication errors. For example, if the infant’s weight is captured incorrectly, improvements in the drug delivery process become irrelevant. If the child’s weight is unavailable, the process, as a whole, is rendered useless.
In response to similar issues for older children, the PTN, under the leadership of Dr. Susan Abdel-Rahman at Children’s Mercy Hospital in Kansas City, recently validated the Mercy TAPE—an anthropometric-based device developed by Dr. Abdel-Rahman that predicts weight in children 2 months through 16 years of age. The critical gap that remains unaddressed by the Mercy TAPE and other weight estimation strategies, is the newborn period. The Baby TAPE study intends to collect the necessary anthropometric data on children under the age of 3 months with the eventual goal of developing, designing, and validating a similar weight estimation tool for newborns and young infants. Anthropometric data on length and girth surrogates was collected in approximately 2000 infants at 8 study sites.
- A Weight Estimation Strategy for Preterm and Full-Term Infants Global Pediatric Health • December 2017. Abdel-Rahman SM, Paul IM, Delmore P, James L, Fearn L, Atz A, Poindexter B, Al-Uzri A, Lewandowski A, Harper B, Smith PB. Weight is the foremost marker of health outcomes in infants; however, the majority of community workers and health care providers in remote, resource-constrained settings have limited access to functional ...
- An anthropometric survey of US pre-term and full-term neonates Annals of Human Biology • December 2017. Abdel-Rahman SM, Paul IM, Delmore P, James L, Fearn L, Atz AM, Poindexter BB, Al-Uzri A, Lewandowski A, Harper BL, Smith PB; Best Pharmaceuticals for Children Act – Pediatric Trials Network. Anthropometric data prove valuable for screening and monitoring various medical conditions. In young infants, however, only weight, length and ...
Susan M. Abdel-Rahmen, PharmD
Children's Mercy Hospital
Kansas City, MO
- Project babyTAPE Measures Up On December 18, 10 days ahead of schedule, the PTN babyTAPE team enrolled its 2,000th participant. On January 29, the babyTAPE databse was locked. The data collected in the babyTAPE study will be used to develop, design, and validate a weight estimation tool, similar to what is pictured, specific to infants. The study is chaired by Dr. Susan ...
- Baby TAPE activates first site Penn State Milton S. Hershey Medical Center became the first site activated to enroll patients into the Baby TAPE study this week. Weight is the foremost marker of health and health outcomes in infants. For infants receiving care in a neonatal intensive care unit, however, it can be nearly impossible to remove or account for the ...