PTN Studies

The PTN conducts Phase 1-4 trials and data-based studies across a broad range of conditions affecting pediatric patients.

ONGOING STUDIES

Study Name Status Population Condition Study Type ClinicalTrials.gov ID
Antibiotic safety (SCAMP) Enrolling Premature infants Intra-abdominal infections Interventional NCT01994993
Anti-epileptic obesity Start-up Obese children Epilepsy Interventional  Pending
Anti-staph trio Enrollment closed; analysis ongoing Premature infants Staphylococcal infections Interventional  NCT01728363
Baby TAPE Analysis ongoing Newborns and young infants NA (Weight estimation tool) Interventional
Baby TAPE III Start-up Newborns and young infants NA (Weight estimation tool) Interventional
Caffeine Analysis ongoing Premature infants and infants Bronchopulmonary dysplasia Retrospective data collection
Furosemide Enrolling Premature infants Bronchopulmonary dysplasia Interventional  NCT02527798
Long-term Antipsychotic Pediatric Safety Trial (LAPS) Start-up Children Mono-antipsychotic therapies Observational
Methadone Enrollment closed; analysis ongoing Children Opiate withdrawal Observational NCT01945736
Midazolam Analysis ongoing Children (≥2 y) Seizures Retrospective data analysis NA
Pantoprazole Enrollment closed; analysis ongoing Obese children GERD Phase 1 NCT02186652
Personal protective equipment (PPE) Start-up Research doctors and nurses Evaluating impact of various PPE Interventional NA
POPS Enrolling Children (<21 y) Various (drugs administered regularly by physicians) Observational  NCT01431326
Sildenafil Enrolling Premature infants Bronchopulmonary dysplasia Phase 1 NCT01431336
Sildenafil II Start-up Premature infants Bronchopulmonary dysplasia Phase 2 Pending
Timolol Start-up Infants Infantile hemangioma Phase 2
Trimethoprim-sulfamethoxazole and clindamycin Analysis ongoing Children Skin and soft tissue infections Data from 3 protocols NCT01431326, NCT01728363, NCT01744730

COMPLETED STUDIES

Study Name Status Population Condition Study Type ClinicalTrials.gov ID
Acyclovir Closed; clinical study report submitted to FDA Premature infants Systemic infection Phase 1 NCT00942084
Acyclovir retrospective Closed; clinical study report submitted to FDA Infants Herpes simplex virus Retrospective data collection
Ampicillin Published; clinical study report submitted to FDA Infants Bacterial infections including sepsis and meningitis Secondary data analysis
Clindamycin obesity Clinical study report submitted to FDA Obese children Staphylococcal infections Phase 1 NCT01744730
Diuretic safety Clinical study report submitted to FDA Infants Bronchopulmonary dysplasia Retrospective observational  NA
Fluconazole safety Published; clinical study report submitted to FDA Infants Candidemia Meta-analysis NCT00734539
Hydroxyurea Clinical study report submitted to FDA Children (2-4 y) Sickle cell anemia or sickle beta-zero thalassemia Phase 2 NCT01506544
Lisinopril PK Clinical study report submitted to FDA Children and adolescents (2-17 y) Kidney transplant; high blood pressure Interventional NCT01491919
Lorazepam Clinical study report submitted to FDA Children and adolescents (3 mo-18 y) Status epilepticus (Status 1) Interventional NCT00114569
Lorazepam or diazepam Clinical study report submitted to FDA Children and adolescents (3 mo-18 y) Pediatric status epilepticus (Status 2) Interventional NCT00621478
Meropenem Published; clinical study report submitted to FDA Infants Intra-abdominal infections Interventional NCT00621192
Metronidazole Published; clinical study report submitted to FDA Premature infants Serious infection caused by anaerobic bacteria Interventional NCT01222585
Obesity informatics Published Children Various Systematic literature review  NA
Pediatrix meta-analysis Published; clinical study report submitted to FDA Infants Various Meta-analysis  NA
TAPE Published; clinical study report submitted to FDA Children (2-16 y) NA (Mercy Method™ for weight estimation) Observational NCT01507090